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Sertraline is a selective serotonin reuptake inhibitor (SSRI) prescribed off-label to treat premature ejaculation. By increasing serotonin levels in the brain, it helps extend the time to ejaculation and may also ease anxiety around performance.
Sertraline helps regulate the brain’s serotonin levels, which play a role in timing of ejaculation. When taken daily, it can reduce hypersensitivity and support longer-lasting sexual performance.
Most people tolerate sertraline well, especially at low doses used for PE. Possible side effects include:
Let your provider know if you experience mood changes or persistent side effects.
Take one tablet by mouth once daily at the same time each day.
It may take 2 to 4 weeks to see full benefits. Do not stop taking suddenly—follow your provider’s guidance for any dosage changes.




Find my treatment


There is no single permanent cure for PE, but many people see long-term improvement with the right treatment plan. Medications, simple techniques, and addressing things like stress or anxiety can make a major difference. Some people need short-term support, while others benefit from continued treatment depending on the cause.
Most people see the best results by combining medical treatment with practical techniques. Medication can help delay ejaculation, and methods like start-stop, squeeze techniques, and slower pacing can help build better control. Improving communication with your partner, lowering stress, and strengthening pelvic floor muscles may also help.
Lifelong PE starts from a person’s earliest sexual experiences and tends to stay consistent over time. Acquired PE begins later, after a period of normal sexual function. Acquired PE is commonly linked to stress, relationship changes, medical conditions, or certain medications.

At Admired, we believe PE care should be discreet, supportive, and focused on your goals. Our licensed providers listen without judgment and work with you to find a treatment that fits your needs, lifestyle, and preferences.
Whether you’re looking to last longer, reduce anxiety, or feel more in control, we’re here to help you perform with confidence. With expert guidance and proven options, you don’t have to figure it out alone.

